DELASOL® - Enteric Capsule Release

Enteric Capsules with

DELASOL^® Gelatin Product

Expanding GELITA’s Portfolio of Capsule Release Possibilities

GELITA offers a comprehensive portfolio of gelatins that provides a broad release profile in soft capsules. Besides a variety of versatile and tailor-made standard gelatins, there is the RXL^® Portfolio for improved capsule shelf-life and stability. These special gelatins provide reliable release and reduced cross-linking properties, even under extreme storage conditions. This GELITA capsule gelatin portfolio is complemented by RAPISOL^® and DELASOL^®. While RAPISOL^® offers a faster release of the fill, DELASOL^® allows the manufacturing of true enteric softgels in only one production step.

Satisfying Consumer Demand

Consumers have been ingesting nutrients in soft capsules for decades due to their ease of swallowing and convenience. However, one nagging issue has been plaguing consumers for as long as they’ve been ingesting fish oil and other omega-3 fatty acids: fishy burps and aftertastes. This undesirable effect has even demotivated the otherwise health-conscious consumers to avoid taking fish oil supplements altogether.

Until now. DELASOL^® – the first commercially available gelatin product of its kind – allows for the one-step production of enteric capsules that open in the intestine (instead of the stomach, as with traditional gelatin capsules).

Added Value with DELASOL^®

Most enteric delivery systems are produced by applying an acid-insoluble coating to freshly produced soft capsules. This intensive two-step process adds time and money to the cost of each enteric capsule. Additionally, this coating produces an opaque shell – which is less desired by consumers.

With DELASOL^®, capsules producers now have the ability to create enteric capsules using existing equipment in a one-step process – avoiding additional time and costs – while creating brilliantly clear capsules.

Proven Enteric Release

DELASOL^®allows manufacturers to produce enteric capsules that adhere to USP (US Pharmacopeia) dissolution parameters. These parameters include:

Capsules will not release more than 10% of the fill during two hours in 37°C simulated gastric fluid
Capsules will be fully dissolved by 45 min in simulated intestinal fluid Dissolution results with 20 oblong enteric fish oil capsules produced with DELASOL^®.
0% of capsules released the fill in simulated gastric acid (representing the stomach)
100% of the capsules showed NO RELEASE (no “leakers”)
2.15 minutes = average time for capsules to release when pH adjusted to represent intestinal fluids

DELASOL^®Add Value to Consumers and Industry

Benefits of DELASOL^®

Promotes consumer compliance by eliminating fishy burps often associated with fish oils
Offers true enteric performance
Reduces additional time and processing steps associated with historic enteric processes
Provides an enteric solution with one product and one process
Although currently available in bovine bone types, GELITA is developing solutions from other raw material sources.