February
15, 2019
5 min

OUTSTANDING PHARMA SOLUTIONS FOR EVERY APPLICATION

As a truly versatile excipient, gelatin can be tailored to provide capsules with a broad spectrum of specific attributes. From rapid release in the stomach to enteric release for fills with an unpleasant aftertaste, GELITA’s Release Profile Portfolio enables soft capsule manufacturers to define the timing and location of fill release. In addition, specific capsule gelatins reduce cross-linking behavior in the capsule and enhance shelf-life stability.

December
14, 2018
3 min

LIVING INNOVATION: THE NOVOTEC® EFFECT

Keen to promote a creative environment and develop ideas, GELITA has implemented a culture of integral innovation that enables every one of its 2500 employees to contribute to the company’s success. Continuous development in every business area is GELITA’s driving force and a key element of such success. Why? Because every innovation starts with just one thought. Or sometimes just a coincidence…

December
03, 2018
4 min

ALL NATURAL? IS HPMC (E464) A CREDIBLE ALTERNATIVE TO GELATIN?

As soon as a product is labeled as "vegetarian" or "vegan," consumers immediately get the impression that there’s something inherently good or natural about it, or that it’s somehow better for their health. However, the recent discussions about vegetarian meat substitutes have shown that this is not necessarily true. Such is the case for HPMC hard capsules. They’re vegan, made from cellulose fiber and therefore regarded as natural. The use of HPMC hard capsules is not just a bonus for vegetarians and vegans, it's also great news for the many consumers who avoid animal products — as long as there’s no perceived disadvantages compared with the animal-based original.

October
02, 2018
3 min

FAST, FASTER, RXL R2 — GET YOUR ACTIVE INGREDIENT TO ITS DESTINATION AT FULL SPEED!

Everyone knows the situation: just before an important meeting or presentation, you’re floored by summer flu. As a consumer, you want rapid results and immediate relief. That means that, as well as a fast-acting active, it’s important that the ingredient can be released as quickly as possible to reach its site of action at full speed. Even the fastest active ingredient is only as quick as its release profile.

September
11, 2018
3 min

A SELF-DEFENSE MECHANISM FOR GELATIN CAPSULES

If you work with soft capsules in the pharmaceutical industry, then you’ll know that cross-linking can occur in certain temperature and humidity conditions, especially with reactive and aggressive fillings. The gelatin can unintentionally form a rigid barrier that prevents the active ingredient within the capsule from reaching its destination at the right time (or at all). If this happens soft capsules become increasingly less soluble over time, resulting in overly long dissolution times in the GI tract and slow release properties.